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Clinical Presentation: Overlapping and Distinct Features Children with both ASD and CFDS often present with a specific clinical profile: Neurological symptoms: seizures, developmental regression, ataxia, hypotonia Behavioral manifestations: irritability, sleep disturbances, and sometimes self-injurious behaviors Physical markers: microcephaly or decelerating head growth Communication challenges: speech delay or regression beyond typical ASD profiles This distinct presentation suggests CFDS may define a specific ASD subgroup rather than being a universal feature of autism

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doi: 10.1111/dom.15911