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Whilst these medications produce significant overall weight reduction, they do not selectively target abdominal fat

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Interestingly, a new version of GLP-1s known as tirzepatide (Mounjaro) may be more effective than semaglutide

There are very few effective medications for substance use disorders, so theres a lot of excitement about whether these drugs could play a role. Why newer drugs are more powerful While early GLP-1 drugs focused on a single receptor, newer medications like tirzepatide activate more than one hormonal pathway

Abstract Glucagon-like peptide 1 receptor agonists (GLP-1RAs) are increasingly being used to treat diabetes and obesity