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Additionally, fatigue was commonly discussed online, despite being less prominent in clinical trial data, while known side effects like nausea were also widely reported

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Second, GLP-1R activation enhances neurovascular coupling function, improves cerebral blood flow and repairs BBB integrity, blocking the penetration of peripheral inflammatory factors into the center (Wong et al., 2024)

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It is known to lower the risks of heart disease by improving cholesterol levels in the blood, thereby protecting against the possibility of stroke and high blood pressure