As an antioxidant, glutathione directly quenches several reactive oxygen species (free radicals)
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MHRA advises restricted use Loperamide for diarrhoea management when appropriate, but should be avoided if blood in stools, fever, or suspected inflammatory/infectious diarrhoea Laxatives for constipation, with macrogol (polyethylene glycol) preparations typically first-line in UK practice, alongside optimising dietary fibre and hydration Dose adjustment strategies include temporarily maintaining a lower dose if gastrointestinal side effects are problematic, allowing additional time for adaptation before escalation
Prioritizing adequate protein intake stands as the foundational intervention
References Lin F, Yu B, Ling B, et al