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Consequently, in vitro experiments reveal that PBM, through close-range efficient irradiation, simultaneously activates the Sox9-centred ECM synthesis pathway while suppressing the inflammation-catabolism pathway mediated by NF-B and others

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Plasma free fatty acid (FFA) concentrations were measured using the Free Fatty Acid Quantification Kit (Sigma-Aldrich) in separate cohorts of mice, including both sexes of whole-body Gpr146/ and Gpr146/ mice on HFD, as well as adipose-specific and liver-specific knockout models following HFD feeding