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Mechanistically, ammonium disrupts acidic compartments, as indicated by reduced LysoTracker staining, likely impairing the pH-dependent maturation of perforin (79)

A Potential Mechanism of Cardio-Renal Protection With Sodium-Glucose Cotransporter 2 Inhibitors: Amelioration of Renal Congestion

Polyploidyenlarged nuclei and/or binuclear hepatocytes are often associated with increased cytoplasmic volume

demonstrated that bovine aortic endothelial cells (BAECs) with deficient G6PD activity, which consequently lowers NADPH levels, exhibit increased oxidative stress in parallel with NO depletion [46]

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