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Our data suggest that the treatment of colon tumor cells with IGF-1R inhibitors stimulates p70S6K1 activity via MEK1/2 to promote survival, providing a new strategy for colorectal cancer therapeutics

Modulation of 4,000+ genes (the gene reset hypothesis) In 2012, Pickart and Margolina published a landmark transcriptomic analysis , they tracked which genes GHK-Cu changes in fibroblasts

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