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Co-localisation of SNAP/FLAG-hGLP-1R with cholesterol in the same cells using the fluorescent D4H*-mCherry probe to label plasma membrane cholesterol at the cytosolic leaflet (32) corroborated our previous results as we measured a significant decrease in co-localisation between GLP-1R V229A and cholesterol under vehicle conditions compared to WT GLP-1R (Figure 3E-G)
Energy balance after Sodiumglucose cotransporter 2 inhibition
doi:10.1111/dom.14725 7
These events trigger downstream signaling pathways, including AKT, Ras (rat sarcoma), and STAT3 pathways, which are required for MET biological activities (Ponzetto et al., 1994
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